Treatments. Treatment for nocturia can sometimes include medication, such as: anticholinergic drugs, which help lessen the symptoms of an overactive bladder. desmopressin, which causes your kidneys to produce less urine at night.

Nocturia may result from several different causes: You produce a great deal of urine (more than 2 liters) a day (polyuria) Your body produces a large volume of urine while you sleep (nocturnal polyuria) You produce more urine at night than your bladder is able to hold (low nocturnal bladder capacity).